Endocrine stress responsivity and social memory in 3xTg-AD female and male mice: A tale of two experiments

ET Nguyen, D Selmanovic, M Maltry, R Morano… - … and Behavior, 2020 - Elsevier
… heightened stress-induced corticosterone levels and … Although 3xTg-AD mice do not
display elevated basal … 3xTg mice (ie, 4 months) already exhibit altered mRNA expression of …

Age-related changes in social behaviours in the 5xFAD mouse model of Alzheimer's disease

F Kosel, PT Munoz, JR Yang, AA Wong… - Behavioural Brain …, 2019 - Elsevier
… Evidence for increased sociability in the 3xTg-AD mouse … accelerated pathology, transgenic
5xFAD mice exhibit deficits … exhibit abnormal responses to social odour cues and altered

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease

JL Hoffman, S Faccidomo, M Kim, SM Taylor… - International review of …, 2019 - Elsevier
… markers of AD pathology in 3xTg-AD mice: 42/40 ratio in the … of alcohol intake altered
spatial learning by 3xTg-AD mice or … of 3xTg-AD mice as a translational approach to increase

Actions of brain-derived neurotrophic factor and glucocorticoid stress in neurogenesis

T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2017 - mdpi.com
altered neurogenesis, and show an interesting effect of GCs: … -transgenic mouse model of
AD (3xTgAD mice expressing … chronic mild social stress, whereas such an elevated and …

[HTML][HTML] Translational modeling of psychomotor function in normal and AD-pathological aging with special concerns on the effects of social isolation

L Castillo-Mariqueo, L Giménez-Llort - Frontiers in Aging, 2021 - frontiersin.org
… the 3xTg-AD/ISO mice subgroup (n = 7) had a high motor … In particular, the grip has been
described as an alteration of … of places, 3xTg-AD mice exhibit these behaviors, which delays the …

[HTML][HTML] Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer's disease-associated markers in 3xTg-AD mice

M Kapadia, MF Mian, D Ma, CP Hutton, A Azam… - Alzheimer's Research & …, 2021 - Springer
… to 3xTg-AD males, 1-year-old 3xTg-AD females still show … in the context of the altered
3xTg-AD phenotype, the current study … In the current study, 3xTg-AD mice exhibited increased

Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer's disease mouse model

L Hoeijmakers, SR Ruigrok, A Amelianchik… - Brain, behavior, and …, 2017 - Elsevier
… in APP/PS1 mice that was altered after ES exposure. APP/PS1 … neuropathology, as
measured by Iba1 and CD11b, was less prominent … -pathology and synapse loss in 3xTg-AD mice

The link between anxiety and Alzheimer's disease: critical facts

S Jain, N Chauhan, S Sharma, KR Reddy… - … in Diagnostic Tools and …, 2020 - Elsevier
… a mouse elevated the and amyloid plaque deposition which was possible due to the
alteration3xTg-AD mice exhibition an activated central stress axis during early-stage pathology …

[HTML][HTML] Impact of social isolation on the behavioral, functional profiles, and hippocampal atrophy asymmetry in dementia in times of coronavirus pandemic (COVID-19 …

A Muntsant, L Giménez-Llort - Frontiers in psychiatry, 2020 - frontiersin.org
… the impact of long-term isolation in male 3xTg-AD mice modeling … isolation in the AD pathology
as related to an increase in … -with-stress strategies were changed (from freeze) to flight …

Effects of Chronic Stress on Anxiety-like Behavior and Fear Learning in the TgF344-AD Rat Model of Alzheimer's Disease

SJ Bouquin - 2020 - digitalrepository.unm.edu
… Importantly, AD patients exhibit altered stress systems and AD-related neuropathology
has … 3xTgAD mice exhibit altered behavior and elevated after chronic mild social stress. …